DuoEXO – Supplement
DuoEXO is a xeno-free, phenol red-free supplement for human mesenchymal stem cell (hMSC) culture.
DuoEXO is optimized for studying and collecting Extracellular Vesicles (EVs). With the extremely low back ground noise, MSCs grow healthily and secreted EVs normally.
Storage : -15°C or below, protect from light.
Shelf Life : 12 months
Avoid freeze / thaw cycles
|Product Name||Catalog Number||Size||Grade|
|DuoEXO – Supplement 50X||RUO003-S||10mL||Research Use Only|
Extracellular Vesicles(EVs) are gaining importance since early 2010s, and MSC derived EVs have been proven to be crucial in wound healing, angiogenesis and immune signaling. However, it’s not easy to collect and purify these EVs, since undesired exosomes are abundant in most MSC culture medium already.
- DuoEXO is an EVs reduced xeno-free cell culture supplement for hMSC. Despite the low background noise, MSCs can secreted EVs and remain healthy for passages. DuoEXO make it easier to collect and study EVs from MSCs with less impurity.
- DuoEXO is manufactured under GMP and ISO 13485 certified factory, and culture performance is tested from batch to batch.
Low background noise (nano-particles) in DuoEXO
A. 10% FBS
B. Brand S, exosome-depleted FBS
C. 10% ultracentrifugation FBS
D. Brand G, serum free medium
E. 5% hPL
The nano-particles in DuoEXO is 100 times smaller than in other medium.
Cells exhibit similar doubling time in either DuoEXO, 10% FBS or 5% hPL
MSCs derived exosomes are detected after culturing using DuoEXO analysis
The result demonstrates that before culture, unidentified exosomes were detected in 5% hPL but not in DuoEXO. And exosomes were detected in DuoEXO after cultured with MSCs.
User manual and more information are available upon request.